N E W   C A S E S

The Use of HEALx Soother Plus in a Severe Head Injury in a Domestic Cat

Anastasia Komnenou, DVM

Before (Day 0) Day 8 Day 20

Day 27 Day 43 Day 55

Day 78

 

A 2-year-old male European cat presented with a severe head wound after it was hit by a car. Because the owners could not afford a surgical skin reconstruction, an attempt was made to heal the wound using only HEALx Soother Plus in combination with systemic antibiotics (3 weeks) and NSAIDs (7 days). The Soother Plus was applied to the wound twice a day and has continued for the last 2.5 months with good results.

The Use of HEALx Soother Plus, Soother Spray and Booster in a Ball Python with Blistering Skin Lesions

Laura Wade, DVM, Dipl ABVP (Avian) and Dawn Trainor
Specialized Care for Avian & Exotic Pets
Lancaster, NY

Before - DAY 90
(The wounds at the onset appeared similar to the Day 90 photographs.)

DAY 106

DAY 189

A 340-g, adult male ball python (Python regius) was surrendered in July because of poor body condition (BCS: 1.5/5) and prolonged anorexia due to unexplained blistering skin lesions. The snake was pale, and there were several patches of fluid-filled pockets that would break open and allow the skin to slough/separate from the body wall; this was most noticeable near the tail. It was suspected that husbandry factors, thermal or chemical burn, or possible bite wounds from prey were the probable cause. Fluid analysis from the blisters showed mostly mononuclear infiltrate with some heterophils and sporadic bacteria (rods). 
   Initial treatment included careful debridement of crusts, antibiotic therapy (an initial enrofloxacin injection followed by ceftazidime and gentamicin), pain therapy (meloxicam) and topical wound therapy (daily soaks in dilute chlorhexidine solution, with topical Silvadene® ointment and protective bandaging). The snake resumed eating 2 days later.
   After 1 week, some new areas of redness had developed but skin sloughing had decreased. Antibiotic and meloxicam injections were continued.  It was decided to switch to daily soaks in dilute F-10 solution (1:500) and HEALx Soother Plus cream topically. A B-complex vitamin injection was given. In addition, HEALx Booster (0.6 ml PO twice weekly) was administered after meals to supplement immune system function.
   By the third week, gentamicin was eliminated and by the fourth week, meloxicam was eliminated. Soaking and bandage changes were reduced to every 72 hours. However, the skin was still very thin and easily torn. Because it was believed there could be some deficiency in collagen formation, vitamin C injections were given, initially as an IM injection then directly into killed prey twice weekly.
   By the beginning of September, ceftazidime was stopped, but the Soother Plus® cream was continued daily, and Booster and vitamin C injections were given twice weekly. By the end of September, F-10 soaking was done every other day, followed by HEALx Soother Spray without bandaging. Vitamin C injections were given directly via a killed mouse weekly.
   By October, the snake had gained 64 g and was improving overall but continued to develop full-thickness lesions, mostly on the right side after shedding. Soother Spray application, twice weekly F-10 soaks and vitamin C and Booster administration were continued every other day (Figs 1-5; Day 90).
   By November, the snake was eating well and shedding twice a month, and new shed-associated lesions were less frequent and less severe. Older lesions were starting to scab and resolve. At this time, soaking and vitamin C therapies were discontinued, and topical treatment was continued daily to several times a week with Soother Spray (Figs 6-9; Day 106).
   The snake’s condition improved slowly over the next 3 months and by February it had a normal shed. By March, the skin lesions were completely healed, and the snake had gained 149 g since presentation (Figs 10-13; Day 189).
   One year later, the snake had grown and had doubled in weight from presentation. To date, the snake is leading a normal life.

The Use of HEALx Soother Plus and Rain on a Lovebird with a Severe Bite Wound

Carlo Manderscheid, Dr med vet
Luxembourg, Germany

Before - Day 0

Day 12

A 3-year-old, female lovebird (Agapornis personatusa) presented with a bite wound on the cheek after being attacked by a cagemate 3 days prior. The wound was severe and crusty and contained dead tissue. The area was cleaned with a combination of HEALx Rain and F-10. The wound was treated with topical application of HEALx Soother Plus cream, and the owner was instructed to continue applying Soother Plus q12h. The bird was not treated with antibiotics or any other modality in order to evaluate the effectiveness of the Soother Plus.

The Use of HEALx Soother Plus on a Bearded Dragon with Exudative Crusts

Victoria Hollifield, DVM and Kathy Waite, LVT
Best Friends’ Veterinary Hospital
Gaithersburg, MD

Before - Day 0

Day 0 (Soother Plus applied)

Day 11

Day 11

A young bearded dragon (Pogona vitticeps) was found outdoors in a dehydrated, emaciated and lethargic condition; it also presented with a shortened maxilla. Initially, it was not possible to determine if the left eye was present. In addition, the animal had avulsed facial skin, exudative crusts on the face, a small puncture wound on its head and Coccidia/pinworm infestations. Its metabolic bone disease condition and the parasites were addressed. Fluids were administered and Critical Care was fed. The face was treated with an application of HEALx Soother Plus twice a day. The crusts were removed, and a functional left eye was revealed. In the weeks that followed, the face slowly returned to normal.

The Use of HEALx Soother Plus on a Cockatiel with a Fracture and Lesions

Stephen Wyler, DVM
Trylon Vet Care PC
Forest Hills, NY

Before - Day 0

Day 29

A 15-year-old, 78-g female cockatiel (Nymphicus hollandicus) was presented with a pathological fracture of the left tibiotarsus. The bird had a history as a chronic egg layer. The animal was placed in a splint and treated with Lupron, Neocal, Baytril and a low dose of Metacam. The splint was removed 46 days later (Day 0) and the leg had an ulcerative lesion and was still unstable. The leg was coated with HEALx Soother Plus cream and a telfa pad and the splint was replaced. The cockatiel was also treated with Clindamycin, Metacam and Pet Tinic. The Lupron and Neocal were continued at the same dose. The bird  was also weaned onto Harrison’s High Potency Fine Grind at this time. The splint was removed 30 days later and leg had healed and had feather regrowth. The cockatiel continues to eat Harrison’s, and Lupron is still being administered to prevent egg laying.

The Use of HEALx Soother Plus and Booster in an African Grey Parrot Self-mutilation Case

Ariana Finkelstein, DVM
San Antonio, TX

Before - Day 0. Right foot with missing digits and nails

Day 4. Bandages were changed daily.

Day 4. The exposed bone was granulated over with a healthy new granulation bed.

Day 11. The toes were healing well and the wounds were granulating.

After

After

A 9-year-old, 409-g African grey parrot (Psittacus erithacus) presented as an emergency for severe self mutilation of its toes. The bird was stabilized, and butorphanol was administered for pain management. Warmed lactated Ringer’s solution (LRS) was given for shock, and the bird’s feet were scrubbed with chlorhexidine. HEALx Soother Plus cream was applied to the area, and the feet were bandaged (ball bandage). The bird was placed in an incubator to allow for further stabilization after which a more complete physical examination was performed (Table 1).
   Surgical correction of the wounds was discussed but declined by the owner; additional treatment options were also declined. The bird was relinquished to our facility. The patient was started on trimethoprim sulfa while the wounds healed; meloxicam (Metacam) was administered for pain and inflammation. Bandages were changed daily under light sedation with butorphanol and midazolam (Fig 2). The wounds were scrubbed with chlorhexidine and rinsed with saline, and Soother Plus was applied. This routine was continued daily for approximately 1 week.
   Within 4 days of starting therapy with Soother Plus, the exposed bone was covered with a healthy new granulation bed (Fig 3).  On Day 4 blood work was performed. The bird was confirmed female by DNA. The chlamydia DNA/PCR test was negative. A complete blood count was performed  (Table 2). The primary rule out was inflammation. A chemistry panel was also performed (Table 3). A decreased A/G ratio with hypoproteinemia and hypoalbuminemia may result from decreased albumin synthesis as observed in hepatic failure or chronic inflammation or increased albumin loss due to renal or gastro­intestinal disease.
   On Day 8 the blood work was repeated (Table 4). Because the WBC continued to increase, itraconazole was added. The bird weighed 419 g and was doing well. On Day 11 the toes were healing well with no evidence of infection, and the wounds were granulating nicely (Fig 4). The bird was able to grip well and use its remaining toes. Bandaging was no longer required. HEALx Booster (0.1 ml PO q24h) was started at this time.
   Blood work was repeated on Day 17 and a lipoprotein panel was added (Table 5). Protein electrophoresis was also repeated, and the total protein improved but the ratios remained the same. The avian profile was repeated and showed normal values for all except mildly elevated cholesterol.

TABLE 1. Results of the Physical Examination
• The bird had good body condition (BCS: 5/9), but was depressed.
• The beak was within normal limits.
• There was blood inside the mouth from the feet.
• Weight: 0.409 kg (0.90 lb)
• Temperature: 104.4°F
• Pulse/heart rate: 320 (HR)
• Respiration rate: 28 RPM
• The remaining exam results were within normal limits.

TABLE 2. Results of the CBC on Day 4
• Leukocytosis: 25,000 (5-11)
• Anemia of chronic disease PCV: 36% (43-55)
• Protein electrophoresis showed decreased A/G ratio and albumin values, and increased beta globulins

TABLE 3. Results of the Avian Profile on Day 4 Normal Chemistry Values
• Calcium, ionized calcium, chloride, phosphorus, glucose, LDH, cholesterol and potassium
Abnormal Chemistry Values
• CPK: >25,000 U/L (100-1500) high
• AST: 1,880 IU/L (10-350) high
• Total protein: 2.8 g/dL (3.0-5.0) low
• Uric acid: 3.4 mg/dL (4-10) low
• Sodium (Na): 156.9 mmol/L (134-152)
• The blood work indicated elevated liver and CPK values as well as elevated WBC.

TABLE 4. Results of the CBC on Day 8
• WBC: 38,000 103/µL (5-11)
• PCV: continued to decrease anemia of chronic disease 28% (43-55)
• Polychromasia and anisocytosis were present.
• Total solids: 3.4 (normal)

TABLE 5. Results of the CBC / Lipoprotein Panel / Avian Profile on Day 17
• Normal HDL and LDL
• Slightly elevated VLDL: 66 (11-60)
• The WBC count was still elevated but improving at 24,000.
• The packed cell volume returned to normal at 46%.
• Total protein returned to normal.
• Cholesterol: 354 mg/dL (175-300)
• CPK returned to normal.

The Use of HEALx Soother Plus and Sunshine Factor for a Dog with Lesions on the Lips

Sergio Sarmiento Valiente, DVM

Before - Day 0

Day 7

Day 7

A Weimaraner breed dog presented with lesions on the lips from a muzzle that was too small. HEALx Soother Plus cream was applied to the lesions twice a day and HEALx Sunshine Factor was added to the diet (1 tsp daily).

The Use of HEALx Booster for a Turtle with Hipovitaminosis A

Sergio Sarmiento Valiente, DVM

Before - Day 0

Day 14

A water turtle presented with blepharitis due to lack of vitamin A in its diet. Due to the absence of vitamin A, the tissues have difficulty regenerating and therefore show signs of otitis, inflammation of the eye lids and pneumonia. A change in diet was recommended and HEALx Booster was added as a daily dietary supplement (1 Tbs/kg food).

The Use of HEALx Booster Concentrate and Booster and Soother Plus for a Canary with Avian Pox

Sergio Sarmiento Valiente, DVM

Before - Day 0

Before - Day 0

Day 14

Day 14

A canary presented with an avian pox virus infection. The bird was treated with a combination of 1 tsp HEALx Booster Concentrate (crushed), 1 Tbs HEALx Booster and 0.5 kg seeds). HEALx Soother Plus cream was to be applied on the lesions twice a day.

The Use of HEALx Soother Plus in a Rabbit with Bumblefoot

Sergio Sarmiento Valiente, DVM

Before - Day 0

Before - Day 0

Before - Day 0

Day 28

Day 28

Day 28

A rabbit presented with a case of bumblefoot likely caused from contact with urine and/or a wet surface. The feet were cleaned and HEALx Soother Plus cream was applied. The owner was advised to change the substrate to a dry material or towels to be changed daily and to mix Sunshine Factor (1 Tbs/kg of pellets) with the animal’s food. Soother Plus cream was applied twice a day for 2 weeks. After 4 weeks, the skin looks healthier and the hair has started to regrow.

The Use of HEALx Booster for Hamster with Skin Lesions

Sergio Sarmiento Valiente, DVM

Before - Day 0

Day 10

Before - Day 0

Day 10

A hamster presented with poor coat quality and irritated skin, probably due to a poor diet. HEALx Booster was added to its diet (1 Tbs/0.5 kg food). The skin issue had resolved and new hair started growing back on Day 10.

The Use of HEALx Soother Plus for Rabbit with a Wound

Sergio Sarmiento Valiente, DVM

Before - Day 0

Before - Day 0

 

Day 10

Day 10

A 10-year-old female rabbit presented with clinical signs of arthritis in the back bone and pelvis and a wound. It was dragging its rear legs and laying on its side throughout the day. We recommended a change in the bedding material to a dry bedding material and HEALx Soother Plus cream was applied twice on the wound.

The Use of HEALx Booster and Soother Plus to Treat Gout in a Budgerigar

Sergio Sarmiento Valiente, DVM

  
Before - Day 0 Day 1

Day 5 Day 7

Day 10 Day 18
After - Day 27 After - Day 27

Gout in birds is expressed as uric acid deposits in joints and membranes. The typical treatment protocol, which has had only limited success, is removal of the deposits. We have started administering HEALx Booster to birds that exhibit signs of gout and have seen promising results.

In this case, a budgerigar was presented with clinical signs of gout; it had lost considerable weight and the prognosis was poor. Booster was administered at the dose of 0.2 ml PO daily mixed with Harrison’s Hand-feeding Formula for 1 week. Thereafter, Booster (1 tsp) was mixed with the seed diet the bird had been eating. At the same time, HEALx Soother Plus cream was applied topically to the bird’s feet daily for the first week. No other treatment was given. The bird recovered by Day 27.


 

The Use of HEALx Soother Plus, Booster and Harrison’s Bird Foods for an African Grey Parrot with a Severe Wound on its Breast

Sergio Sarmiento Valiente, DVM

  
Before Day 14

Day 14 - Soother Plus gauze applied Day 14 - Gauze applied

Day 21 Day 28
Day 35 Day 42

A male African grey parrot (Psittacus erithacus) presented with a severe open wound on the breast.

The wound was cleaned daily with a sterile saline. A generous amount of HEALx Soother Plus cream was applied topically and covered with strips of gauze. The gauze was applied to the wound and covered with a fine layer of plastic film to keep the cream in place. The breast was then dressed with soft co-adhesive material. The Soother Plus and gauze treatment was changed every 3 days for the first 2 weeks, and then every 4-6 days for the next 3 weeks.

From Day 1 the African grey was fed Harrison’s High Potency Coarse mixed with HEALx Booster (1 tsp/1 lb of food). The bird did not have any difficulty converting to the new diet.

On Day 42 the wound had healed. We believe both the topical treatment and diet were the key in resolving this difficult case where 9 out of 10 veterinarians would have chosen to euthanize this bird.

The Use of HEALx Soother Plus, Soother Spray and Booster in a Severe Bite Wound/Wing Amputation in a Swan

Sergio Sarmiento Valiente, DVM

  

A male swan was attacked by a dog at a safari park. A bite on its wing resulted in a broken right humerus. The wing was amputated by another veterinarian, and the animal was sent back to the swan house.

Four days later when the swan was examined, a serious infection was discovered, which was decomposing the wing. The bird was transferred to the hospital for an emergency surgery to counteract the rapidly declining health and the possibility of death. Surgery was performed to amputate the wing at the shoulder level; there was sufficient skin to close the area.

HEALx Soother Plus cream was applied over the skin to help with pain and healing. Antibiotics and analgesics were administered for 24 hours. The swan was released back to its mate at the safari park the next day with instructions to the staff to: 1) mist Soother Spray daily over the wound and sutures for 10 days; 2) apply Soother Plus directly to the wound daily for 10 days; and 3) Mix HEALx Booster with the swan’s diet (1 Tbls/1 lb food). The swan’s wound completely healed.


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